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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.ischemia.In this study, we demonstrate that BXTY ameliorates myocardial ischemia by activating the soluble guanylateThe results showed that BXTY alleviated the symptoms of myocardial ischemia induced by pituitrin in miceIn conclusion, BXTY can improve the symptoms of acute myocardial ischemia in mice, and activating the

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission

Frontiers of Medicine doi: 10.1007/s11684-023-0983-0

Abstract: Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission

Keywords： mitochondrial fission Ca     Berberine alleviates myocardial     murine model HFpEF    

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Evaluation of the effect of myocardial perfusion after percutaneous coronary intervention in coronaryartery disease by using intracoronary myocardial contrast echocardiography and two other angiographic

WANG Hong, HUANG Lan, JIN Jun, SONG Yaoming, GENG Zhaohua, YU Xuejun, QIN Jun, ZHAO Gang, GAO Yunhua, LIU Zheng

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 62-67 doi: 10.1007/s11684-007-0013-7

Abstract: Detection of abnormal myocardial perfusion is crucial to the prognosis of patients with coronary arteryThe objective of this study is to evaluate the effect of myocardial perfusion by three different methodsintra-coronary myocardial contrast echocardiography (ICMCE), corrected thrombolysis in myocardial infarctionblood volume, reperfusion velocity and myocardial blood flow, respectively.The myocardial blood volume and the myocardial blood flow of the IC-MCE quantitative parameters were
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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract: ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusionthe allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemiaallograft restored blood flow without second reperfusion and cold preservation after 9 min of warm ischemia

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 197-205 doi: 10.15302/J-FASE-2018245

Abstract: activity of rats in an open-field test, which was associated with attenuated neuronal damage induced by ischemiaserum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemiaTaken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative

Keywords： cerebral ischemia     GABA     neuroprotection     leonurine     SOD    

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failure and left ventricular systolic dysfunction in non-diabetic patients with ST-segment elevation myocardial

Hui Wang, Yang Zhang, Zhujun Shen, Ligang Fang, Zhenyu Liu, Shuyang Zhang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 70-78 doi: 10.1007/s11684-020-0749-x

Abstract: Recent studies have shown that acute blood glucose elevation in patients with ST-segment elevation myocardial

Keywords： myocardial infarction     percutaneous coronary intervention     diabetes mellitus     fasting glucose     heart failure    

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Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 317-322 doi: 10.1007/s11684-010-0035-4

Abstract: The inhibitory effect of different reperfusion periods 45 min following hepatic ischemia on the expressionrandomly divided into four groups: normal control group (CO group), sham-operated group (SO group), ischemiaIt is suggested that the digestive tract congestion injury caused by liver ischemia can upregulate the

Keywords： hepatic ischemia-reperfusion     digestive tract congestion     cholecystokinin     vasoactive intestinal peptide    

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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract: Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental ischemia/reperfusion (I/R) injury in pulmonary, intestinal, and myocardial tissue.The first group was the control group; the second group was the vehicle-treated hepatic ischemia/reperfusionA portal triad was created to induce ischemia with a vascular atraumatic clamp.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 433-437 doi: 10.1007/s11684-007-0085-4

Abstract: The effect of peripherally administered oxytocin (OT) on gastric ischemia-reperfusion injury (GI-RI)The animal GI-RI model was established by clamping the celiac artery for 30 min to induce ischemia andresults indicated that the oxytocin could significantly protect gastric mucosal against injury induced by ischemia-reperfusion

Keywords： control     significant difference     surgical     statistical significance     Sprague-Dawley    

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Protective effect of tanshinone II A on signal transduction system protein kinase B in rats with myocardial

Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 431-436 doi: 10.1007/s11684-009-0088-4

Abstract: The effects of tanshinone II A on cell signal transduction system protein kinase B in rats with myocardialRat models of myocardial hypertrophy were established by using abdominal aorta partial coarctation methodMyocardial fiber diameter (MFD) was examined by Hematoxylin-Eosin (HE) staining, and the contents ofIt was suggested that tanshinone II A could prevent myocardial hypertrophy by its action on the Akt signaling

Keywords： tanshinone II A     myocardial hypertrophy     rat     protein kinase B     abdominal aorta coarctation    

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Influence of retinoic acid on TBX1 expression in myocardial cells induced by Shh and Fgf8

Miao LIU, Xiaoyan WU, Jiawei XU, Runming JIN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 61-66 doi: 10.1007/s11684-009-0007-8

Abstract: study was to explore the regulatory mechanism of retinoic acid (RA) on the TBX1 gene expression in myocardialThe expression of Shh and Fgf8 at mRNA and protein levels in neonatal rat myocardial cells were measuredtreated with 3×10 mol/L RA, we observed that the expression of Shh mRNA and protein in neonatal rat myocardialThe results indicated that RA could induce the expression of Shh and Fgf8 in neonatal rat myocardial

Keywords： retinoic acid     Tbx1 protein     Shh protein     Fgf8 protein    

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Assessment of global and regional left ventricular twist and displacement in anterior myocardial infarction

Wei HAN MM, Ming-Xing XIE MD, Qing LV MD, Xin-Fang WANG MD, Li ZHANG MM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 71-76 doi: 10.1007/s11684-010-0006-9

Abstract: evaluate the global and regional left ventricular twist by 2D strain in patients with anterior wall myocardial

Keywords： echocardiography     twist     two-dimensional strain imaging     coronary artery disease    

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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 87-92 doi: 10.1007/s11684-007-0017-3

Abstract: The aim of this paper is to explore the effect of intestinal ischemia/reperfusion (I/R) injury on leptinintestinal I/R injury model of rats was made; the rats were grouped according to the time of after 60 min ischemiaCompared with the levels before the injury, serum leptin in 60 min ischemia/30 min reperfusion (I60´R30

Keywords： significant difference     intestinal I/R     transcriptase-polymerase     metabolic     central secretory    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: barrier destruction is widely observed among patients receiving liver transplant and suffering from ischemia

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Application of Biomaterials in Cardiac Repair and Regeneration Review

Zhi Cui,Baofeng Yang,Ren-Ke Li

Engineering 2016, Volume 2, Issue 1,   Pages 141-148 doi: 10.1016/J.ENG.2016.01.028

Abstract:

Cardiovascular disease is a leading cause of death throughout the world. The demand for new therapeutic interventions is increasing. Although pharmacological and surgical interventions dramatically improve the quality of life of cardiovascular disease patients, cheaper and less invasive approaches are always preferable. Biomaterials, both natural and synthetic, exhibit great potential in cardiac repair and regeneration, either as a carrier for drug delivery or as an extracellular matrix substitute scaffold. In this review, we discuss the current treatment options for several cardiovascular diseases, as well as types of biomaterials that have been investigated as potential therapeutic interventions for said diseases. We especially highlight investigations into the possible use of conductive polymers for correcting ischemic heart disease-induced conduction abnormalities, and the generation of biological pacemakers to improve the conduction pathway in heart block.

Keywords： Myocardial infarction     Heart regeneration     Biomaterial     Tissue engineering     Stem cell    

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Title Author Date Type Operation

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission

Journal Article

Evaluation of the effect of myocardial perfusion after percutaneous coronary intervention in coronaryartery disease by using intracoronary myocardial contrast echocardiography and two other angiographic

WANG Hong, HUANG Lan, JIN Jun, SONG Yaoming, GENG Zhaohua, YU Xuejun, QIN Jun, ZHAO Gang, GAO Yunhua, LIU Zheng

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Journal Article

failure and left ventricular systolic dysfunction in non-diabetic patients with ST-segment elevation myocardial

Hui Wang, Yang Zhang, Zhujun Shen, Ligang Fang, Zhenyu Liu, Shuyang Zhang

Journal Article

Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Journal Article

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Journal Article

Protective effect of tanshinone II A on signal transduction system protein kinase B in rats with myocardial

Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,

Journal Article

Influence of retinoic acid on TBX1 expression in myocardial cells induced by Shh and Fgf8

Miao LIU, Xiaoyan WU, Jiawei XU, Runming JIN

Journal Article

Assessment of global and regional left ventricular twist and displacement in anterior myocardial infarction

Wei HAN MM, Ming-Xing XIE MD, Qing LV MD, Xin-Fang WANG MD, Li ZHANG MM,

Journal Article

Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Application of Biomaterials in Cardiac Repair and Regeneration

Zhi Cui,Baofeng Yang,Ren-Ke Li

Journal Article